Kleenex Anti-Viral Tissues are designed to kill 99.9% of cold and flu viruses*. Each facial tissue is made with a specially treated middle layer that wipes out cold and flu viruses* in the tissue in 15 minutes. When moisture hits the middle blue-dot layer, it will kill 99.9% of viruses in the tissue*. Not only that, but these tissues are made with 3 thick layers. Each tissue box contains 55 total 3-ply tissues and comes in various colors and designs that blend with any home. When you need more than just a tissue, grab Kleenex. Packaging may vary. (*Virucidal Against: Rhinoviruses type 1A and 2 (Rhinoviruses are the leading cause of the common cold), Influenza A virus and Influenza B virus (causes the flu); H1N1 (formerly called swine flu); Respiratory Syncytial Virus (RSV – the leading cause of lower respiratory tract infection in children))